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Table 5 Adverse effects in 99 patients

From: Rapamycin and its analogues (rapalogs) for Tuberous Sclerosis Complex-associated tumors: a systematic review on non-randomized studies using meta-analysis

Adverse effect Percentage of patients
Oral ulcer 54.5
Hypertriglyceridemia 28.3
Upper Respiratory Tract Infection 26.3
Acne/Acneiform Dermatitis 19.2
Sinusitis 16.2
Proteinuria 16.2
Hypercholesterolemia 15.2
Tinea/Other Skin problem 14.1
Leucocytosis 14.1
Diarrhoea 12.1
Anemia 12.1
Otitis Media 10.1
Pyrexia 8.1
Cellulitis 8.1
Joint pain 8.1
Urinary Tract Infection 7.1
Headache 6.1
Lymphopenia 6.1
Increased Alkaline Phosphatase 5.1
Irregular menses 5.1
Nose bleeding 5.1
Gastroenteritis 4
Otitis Externa 4
Incerased ALT, SGPT 4
Gastric Infection 3
Cough 3
Increased Creatinine Kinase 3
Peripheral Oedema 3
Fatigue 3
Vomiting 2
Gingival Hypertrophy 1
Myalgia 1
Acute Pyelonehpritis 1
Dry skin 1
Depression 1
Weight gain 1
Hypothyroidism 1
Retinal tear 1