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Table 1 Summary of PWS patient characteristics and overview of their laboratory and PSG results

From: Evaluation of the hypothalamic-pituitary-adrenal axis and its relationship with central respiratory dysfunction in children with Prader-Willi syndrome

# Age (y) at start of GH GH Status Age (y) at the test ITT/GT Peak cortisol (μg/dl) Cortisol increase (μg/dl) Δ (y) age at PSG and age at test BMI z-score at PSG CA index OA index Tonsil-lectomy
1 1,9 normal 1,7 GT 30,78 23,07 - - - - -
2 2 GHD 1,8 GT 41,98 32,17 −0,76 −0.5 0,7 0 1
3 3,8 normal 2,9 GT 26,5 9,0 - - - - -
4 5 normal 3,3 GT 20,6 12,6 - - - - -
5 3,4 GHD 3,4 GT 39,3 27,3 0,34 3.6 0,1 15 1
6 5,4 GHD 5,4 GT 31,4 18,7 1,71 2.9 0,1 13,4 1
7 12,1 normal 12 GT 20,2 15,84 - - - - -
8 8,5 GHD 14,4 ITT 16,6 9,97 −1,82 1.4 0,6 0,4 3
9 1 normal 0,8 GT 38,32 18,75 −0,22 −2.1 1,9 0,1 3
10 4,2 GHD 3,5 ITT 33,11 13,07 0,5 5.7 5,1 0 3
11 3,8 GHD 3,7 GT 47,1 19,9 0,05 −0.2 0,7 0,5 1
12 5 normal 4,4 ITT 23,45 16,4 - - - - -
13 5,2 normal 4,7 ITT 30,83 20,07 - - - - -
14 6,9 normal 5,5 GT 26.3 19.44 - - - - -
    5,6 ITT 24.0 16.92 - - - - -
15 2,9 normal 5,9 GT 31,5 24,69 −3,08 −0.8 0 4,2 3
16 6,2 GHD 6 GT 26,34 18,28 0 0.9 2,8 0,3 3
17 5,5 GHD 7,7 ITT 26,82 22,9 0,27 3.9 0,6 0,2 2
18 NA GHD 9,4 GT 23,6 17,09 - - - - -
19 13,9 normal 12,2 ITT 29,3 12,5 - - - - -
20 5,4 GHD 14,7 GT 20,88 17,33 −1,02 3.1 1,2 0,5 3
  1. y years, GH Growth Hormone, ITT insulin tolerance test, GT glucagon test; cortisol increase was calculated between the lowest cortisol and the highest cortisol level during the stimulation test, PSG polysomnography, BMI body mass index, CA index central apnea index (#/hour), OA index obstructive apnea index (#/hour), NA not applicable; tonsillectomy:1 = performed after PGS, 2 = before PGS, 3 = no tonsillectomy