Idiopathic (primary) achalasia: a review

Table 1 Effect of botulinum toxin on achalasia

Study	Method	Number of patients enrolled	% LES pressure decreased post treatment	Remission rate at 1 months	Remission rate at 6 months	Remission rate at 12 months
Pasricha et al. [87]	Randomized control trial	21	33 %	90 %	44 %	___
Fishman et al. [92]	Prospective study	60	___	70 %	___	36 %
Gordon et al. [123]	Prospective study	16	___	75 %	48 %	___
Vaezi et al. [2]	Randomized trial	24	1 %	60 %	50 %	32 %
Annese et al. [116]	Randomized trial	16	49 %	100 %	___	12.5 %
Pasricha et al. [94]	Prospective study	31	45 %	90 %	64 %	___
Martinek et al. [124]	Prospective cohort study	49	65 %	93 %	___	41 %
Zaninotto et al. [125]	Randomized controlled trial	40	___	___	66 %	34 %

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