Idiopathic non-cirrhotic portal hypertension: a review

Table 2 Associated conditions in 4 recently reported series of European patients with idiopathic non-cirrhotic portal hypertension

Reference	Hillaire et al. [6]	Cazals-Hatem et al. [11]	Schouten et al. [10]	Siramolpiwat et al. [2]
Prothrombotic disorder	6 PS deficiency	3 PS deficiency	3 PS deficiency	1 PS deficiency
	2 PC deficiency	3 PC deficiency	3 PC deficiency	2 FII Leiden
		2 MTHFR mutation	1 MTHFR mutation	1 FV Leiden
		3 FII Leiden	2 FV Leiden	1 FV Leiden
Haematological malignancy	1	0	4	5
Myeloproliferative neoplasm	6	10	3	0
Chronic HIV infection	0	0	5	15
Autoimmune disorder	3	10	1	9
Crohn’s disease	0	0	3	0
Genetic disorder	0	0	4	0
Solid organ malignancy	0	0	1	0
Azathioprine treatment	0	0	8	0
Arsenicals	-	0	4	0
No associated conditions	12	31	26	30
Incomplete evaluation	2	-	-	9
Total^a	28	59	62	69

FII factor II, FV Leiden factor V Leiden, HIV human immunodeficiency virus, MTHFR metilentetrahydorfolate reductase, PC protein C, PS protein S
(^a): Some patients have more than one associated condition