Expression profiling of white sponge nevus by RNA sequencing revealed pathological pathways

Table 2 GSEA analysis of a WSN patient

Number	Upregulated on WSN	Size	ES	NES
1	MONOOXYGENASE_ACTIVITY	17	0.76	1.85
2	JAK_STAT_CASCADE	21	0.69	1.8
3	EXTRACELLULAR_REGION_PART	216	0.47	1.8
4	SUGAR_BINDING	22	0.69	1.79
5	CARBOHYDRATE_BINDING	45	0.59	1.79
6	LIPID_RAFT	15	0.73	1.75
7	PROTEASE_INHIBITOR_ACTIVITY	21	0.66	1.72
8	POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	17	0.67	1.67
9	NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS	21	0.66	1.67
10	PROTEINACEOUS_EXTRACELLULAR_MATRIX	65	0.51	1.67
11	RAS_GTPASE_BINDING	17	0.68	1.66
12	EXTRACELLULAR_REGION	281	0.43	1.66
13	STRUCTURAL_CONSTITUENT_OF_MUSCLE	15	0.7	1.66
14	EXTRACELLULAR_MATRIX	66	0.51	1.65
15	COAGULATION	31	0.58	1.65
16	POSITIVE_REGULATION_OF_TRANSLATION	22	0.62	1.65
17	VIRAL_REPRODUCTIVE_PROCESS	22	0.62	1.64
18	EXTRACELLULAR_SPACE	155	0.44	1.63
19	BLOOD_COAGULATION	30	0.58	1.62
20	PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY	29	0.59	1.62

ISSN: 1750-1172