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Table 2 Prevalence of pemphigus and pemphigoid autoantibodies in healthy blood donors

From: Prevalence of pemphigus and pemphigoid autoantibodies in the general population

Antigen IIFM positive* [n] IIFM positive* [%] ELISA**
Negative [n] Below diagnostic cut-off [n] Above diagnostic cut-off (≥20 RU/ml) [n]
Dsg1# 15 0.21 (0.11-0.32) 8 6 1
Dsg3# 7 0.10 (0.03-0.17) 1 6 0
BP180-NC16A§ 37 0.52 (0.36-0.69) 2 19 16
BP230# 3 0.04 (0.00-0.09) 1 2 0
  1. *From a total of 7063 samples. Numbers in parentheses correspond to a 95 % confidence interval. This table contains double positives. **All IIF-positive samples were included (15 for Dsg1, 7 for Dsg3, 37 for BP180-NC16A, 3 for BP230). #Transfected HEK cells expressing recombinant antigen. §Purified spotted protein. Abbreviations used: IIFM, indirect immunofluorescence microscopy