Fig. 2
From: Prevalence of pemphigus and pemphigoid autoantibodies in the general population
Anti-BP180-NC16A autoantibodies from healthy individuals induce ROS release from neutrophils. (a) ROS release of immune complex-activated PMN in relation to cells incubated with antigen only. Owing to the non-parametric distribution, the data are presented as the median (line), 25/75-percentile (boxes), 5/95-percentiles (error bars) and outliers (dots). *p < 0.05 (ANOVA on ranks followed by Dunn’s method for multiple comparisons versus control (NC16A-negative samples). (b) Concentrations of anti-BP180-NC16A IgG correlate with the amount of ROS release from PMN (r = 0.786, p < 0.001, Pearson product-moment correlation)