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Table 2 Comparison of clinical features of 81 patients with good or poor outcomes

From: Inflammatory myopathy with anti-signal recognition particle antibodies: case series of 100 patients

  Good outcome Poor outcome p
  (n = 59) (n = 22)  
Females 35 (59 %) 16 (73 %) 0.3
Age at disease onset ≤ 15 years 1 (2 %) 6 (27 %) 0.0003
Disease progression > 12 months 12 (20 %) 8 (36 %) 0.1
Clinical characteristics    
 Legs predominantly than arms 43 (73 %) 16 (73 %) 1.0
 Severe limbs weakness 31 (53 %) 20 (91 %) 0.001
 Neck weakness 37 (63 %) 17 (77 %) 0.2
 Dysphagia 20 (34 %) 14 (63 %) 0.02
 Muscle atrophy 32 (54 %) 20 (91 %) 0.002
 Decreased deep tendon reflex 28 (47 %) 15 (68 %) 0.1
 Myalgia 19 (32 %) 7 (32 %) 1.0
 Interstitial lung disease 12 (20 %) 0 (0 %) 0.02
Laboratory findings    
 Creatine kinase (IU/L) 6181 ± 4313 7079 ± 5263 0.5
 Elevated C-reactive protein 7 (12 %) 8 (36 %) 0.01
 Anti-SRP54 antibody index 1.4 ± 1.0 1.3 ± 1.1 0.8
 Lymphocyte infiltration in histology 11 (19 %) 3 (14 %) 0.6