GD Type 1 (N = 99) | ||
---|---|---|
Number of events | Number (%) of patients with at least 1 GD-related event | |
All events | 64 | 39 (39.4%) |
Bone events | 8 | 8 (8.1%) |
Bone infarction | 4 | 4 (4.0%) |
Osteonecrosis | 1 | 1 (1.0%) |
Femur fracture | 1 | 1 (1.0%) |
Hand fracture | 1 | 1 (1.0%) |
Rib fracture | 1 | 1 (1.0%) |
Other spontaneously reported events | ||
Hematological events | 12 | 11 (11.1%) |
Thrombocytopenia | 5 | 5 (5.1%) |
Pancytopenia | 1 | 1 (1.0%) |
Epistaxis | 3 | 3 (3.0%) |
Gingival bleeding | 1 | 1 (1.0%) |
Platelet count decreased | 1 | 1 (1.0%) |
Haematoma | 1 | 1 (1.0%) |
Visceral events | 4 | 3 (3.0%) |
Hepatomegaly | 2 | 2 (2.0%) |
Hepatosplenomegaly | 1 | 1 (1.0%) |
Splenomegaly | 1 | 1 (1.0%) |
Other frequent events (incidence ≥3%)* | 24 | 19 (19.2%) |
Asthenia/Fatigue | 8 | 8 (8.1%) |
Serum ferritin increased | 5 | 5 (5.1%) |
Chitotriosidase increased | 4 | 4 (4.0%) |
Bone pain | 4 | 4 (4.0%) |
Osteopenia | 3 | 3 (3.0%) |