Table 1 Characteristics of investigated populations
From: A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease
Cohort | Individuals ( n ) | Measurements ( n ) | Age (first value) | Males ( n ) | Females ( n ) |
|---|---|---|---|---|---|
(median, IQR, number of cases) | Age (median, IQR) | Age (median, IQR) | |||
NPC1 patients | 110 | 241 | 13 (4-20) | 33 | 33 |
(n = 67) | 13 (4-19) | 12 (5-23) | |||
NPC1 carriers | 63 | 94 | 46 (25-54) | 8 | 12 |
(n = 20) | 48 (27-56) | 45 (14-53) | |||
NP-A/B patients | 21 | 21 | 9 (1-15) | 10 | 4 |
(n = 14) | 7 (1-15) | 11 (3-47) | |||
NP-A/B carriers | 5 | 5 | 7 (min-max: 2-35) | 1 | 2 |
(n = 3) | 7 yrs | Med.: 19 | |||
Healthy controls | 43 | 47 | 41 (20-50) | 3 | 9 |
(n = 12) | 51 (min-max: 4-71)) | 38 (21-46) |