Table 1 Patient demographic and clinical characteristics
Characteristic | All patients (N = 52) |
|---|---|
Gender | |
Male | 52 |
Age, ya | |
Mean (SD) | 12.4 (9.2) |
Median (min, max) | 11.0 (1.3, 51.0) |
Age, y, category, n (%)a | |
<2 | 1 (2.0) |
2-5 | 5 (9.8) |
5-10 | 17 (33.3) |
10-15 | 16 (31.4) |
15-18 | 4 (7.8) |
18-29 | 4 (7.8) |
≥30 | 4 (7.8) |
Age at diagnosis, Mean (SD) | 3.5 (2.7) |
Years since diagnosis, y (n = 47)b | |
Mean (SD) | 9.3 (8.4) |
Median (min, max) | 6.8 (0.7, 46.9) |
Severe patients | |
Mean (SD) | 6.7 (5.4) |
Median (min, max) | 5.2 (0.7, 27.5) |
Attenuated patients | |
Mean (SD) | 14.3 (11.0) |
Median (min, max) | 11.9 (1.7, 46.9) |
Family history of MPS II | |
Yes | 17 (32.7) |
If yes, prenatal diagnosis | 1 (5.9) |
No | 31 (59.6) |
Do not know | 4 (7.7) |
MPS II Classification, n (%)c | |
Severe (with cognitive impairment) | 36 (69.2) |
Attenuated (without cognitive impairment) | 16 (30.8) |
Living Situation, n (%) | |
Living with parents | 48 (92.3) |
Living alone | 3 (5.8) |
Living in an institution during the week | 1 (1.9) |