Figure 4
From: Germline SMARCA4 mutations in patients with ovarian small cell carcinoma of hypercalcemic type
A pedigree of the proband’s 2 family. The proband (P, II:1) with SCCHT had a germline mutation in SMARCA4 exon 16 (c.2352insG), while her brother (II:2) turned out to be unaffected. The proband’s parents (I:1, I:2) and her second brother (II:3) refused to attend the study. (+/−) heterozygous mutation carrier in the germline; (+/+) wild-type in the germline. A diagonal line through a symbol indicates that the person is deceased.