Figure 3
From: The genotypic and phenotypic spectrum of PIGA deficiency
PIGA expression and surface expression of GPI-AP (CD109) in patient skin fibroblasts. (A) Western Blot showing similar expression of PIGA in patient versus control fibroblasts; β-actin was used as a loading control. (B) Flow cytometry analysis of patient’s fibroblasts revealed reduced expression (56%) of GPI-AP (CD109) when compared to control fibroblasts. Isotype controls are included to show specific binding.