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Table 5 Correlation between hyposalivation and its causes and consequences in study group (with NF1)

From: High prevalence of hyposalivation in individuals with neurofibromatosis 1: a case–control study

Variables

Hyposalivation

UWSFR

OR (95% IC)

P *

Age

43 ± 15.6

0.77

Female/Male

23/6 (3.8/1)

2.5 (0.7-9.0)

0.14

Plexiform neurofibroma close to or involving major salivary glands areas

1 (3.4%)

0.2 (0.01-2.1)

0.29

Smoker

1 (3.4%)

0.2 (0.01-2.1)

0.29

Alcohol user

5 (17%)

1.1 (0.2-5.6)

1.0

Hyposalivation-inducing drugs

15 (51%)

1.6 (0.5-5.0)

0.41

Intake less than 2 liters of liquid daily

8 (27%)

1.7 (0.5-5.6)

0.36

Caffeinated or stimulant drink use

13 (44%)

1.2 (0.3-4.1)

0.68

Mouth breather

14 (48%)

1.4 (0.4-4.8)

0.51

Oral candidiasis

7 (24%)

1.2 (0.3-5.0)

1.0

Tongue coating index

44.4 ± 27.3

0.05

  1. UWSFR, Unstimulated whole saliva flow rate; OR (95% IC), Odds ratio and 95% of confidence interval.
  2. *P value is from Qui-square analysis and Fisher’s exact tests for categorical variables and Mann–Whitney test for numerical variables; Results of age and tongue coating index indicate mean ± standard deviation.