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Table 1 Baseline disease data

From: Tolerance and efficacy of off-label anti-interleukin-1 treatments in France: a nationwide survey

Disease

No. of patients

M/F

Median age * (y) (IQR, TR)

Median disease duration * (y) (IQR)

AOSD

35

12/23

40.9 (22.4, 21.4-79.4)

4.4 (7.4, 0.04-46.9)

Gout

28

24/4

57.4 (11.5, 29.0-86.3)

1.6 (8.5, 0.03-37.2)

SJIA

27

17/10

7.3 (9.35, 2.1-29.1)

1.4 (5.2, 0.11-24.1)

CAPS

21

11/10

25.9 (22.5, 3.8-66.3)

20.7 (25.3, 0.5-54.7)

FMF

14

4/11

21.1 (33.7, 5.9-60.8)

13.1 (19.5, 5.3-42.9)

MKD

12

5/7

9.5 (14.9, 1.4-36.1)

9.5 (15.6, 0.83-34.9).

SAPHO

9

4/5

49.1 (18.8, 25.2-59.0)

10.6 (14, 1.2-26.3)

Schnitzler’s syndrome

7

5/2

55.3 (22.0, 49.9-76.2)

7.4 (6.2, 3.5-13.7)

Spondyloarthritis

5

4/1

44.1 (18.9, 31.2-72.5)

10.3 (7.3, 5.1-13.4)

Vasculitis

4

3/1

69.5 (18.6, 58.7-83.6)

6.7 (6.1, 3.8-15.9)

Chondrocalcinosis

4

1/3

67.9 (18.8, 46.8-83.6)

3.7 (2.8, 0.5-10.4)

GPP

3

2/1

55.5 (21.1, 44.3-72.4)

17.1 (13.4, 8.5-35.5)

Polychondritis

3

1/2

42.2 (27.5, 29.8-66.4)

9.1 (10.9, 8.3-30.1)

TRAPS

3

1/2

47.8 (29.5, 12.5-51.7)

31.2 (19.1, 9.3-47.5)

  1. *At time of anti–IL-1 treatment onset.
  2. M: male, F: female, AOSD: adult-onset Still’s disease, sJIA: systemic juvenile idiopathic arthritis, CAPS: cryopyrin-associated periodic syndrome, FMF: familial Mediterranean fever, MKD: mevalonate kinase deficiency, SAPHO: synovitis, acne, pustulosis, hyperostosis, osteitis, GPP: generalized pustular psoriasis, Vasculitis: giant cell arteritis (2) and polyarteritis nodosa (2), TRAPS: tumor necrosis factor receptor-associated periodic syndrome, IQR: interquartile range, TR: total range.