Table 1 The distribution of underlying diseases in 85 patients with HLH

Infection

29 (34.1%)

Viral infection

EBV

10

CMV

2

Herpes virus

1

HIV

1

Sepsis

Staphylococcus aureus

2

Klebsiella pneumoniae

4

aeruginosa

1

Pulmonary infection

Candida albicans

1

Klebsiella pneumoniae

3

Unknown

2

Intestinal infection

Escherichia coli

2

Autoimmune disorders

6 (7.1%)

Rheumatoid arthritis

2

Systemic lupus erythematosus

2

Adult Still’s disease

2

Malignancy

23 (27.1%)

Aggressive NK cell leukemia

2

B-cell lymphoma

3

T&NK cell lymphoma

17

T lymphoblastic leukemia

1

Unknown causes

27 (31.8%)