Mutation negative a (N = 224) | Mutation positive (N = 34) | p-value | |
---|---|---|---|
Age (years) | 41.8 (17.0) | 31.9 (19.5) | 0.004 |
Female gender | 63/224 | 17/34 | 0.01 |
TAD | 199/224 | 29/34 | 0.55 |
DAD | 52/224 | 5/34 | 0.27 |
Family history for TAD | 52/179 | 15/28 | 0.01 |
Systemic score | |||
1-2 | 47/164 | 3/33 | 0.018 |
3-6 | 45/164 | 9/33 | 0.98 |
≥7 | 13/164 | 10/33 | <0.001 |
Mitral valve prolapse | 23/216 | 7/34 | 0.097 |
Bifid uvula | 2/139 | 2/15 | 0.048 |
Hypertelorism | 5/224 | 3/34 | 0.039 |
Arterial tortuosity | 12/77 | 0/7 | 0.26 |
Skin a/o facial features vEDS | 15/142 | 2/19 | 0.99 |