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Table 2 Clinical features and hemodynamic parameters of patients with each TPRC6 polymorphism

From: Molecular and clinical analysis of TRPC6 and AGTR1 genes in patients with pulmonary arterial hypertension

Clinical features and hemodynamic parameters Carriers of c.1-361A > T mutation Carriers of c.1-254C > G mutation Carriers of c.1-218C > T mutation
Clinical data p-value Clinical data p-value Clinical data p-value
Number 32   37   32  
Gender 25 F/7 M 0.002 23 F/14 M 0.177 11 F/21 M 0.035
Age at diagnosis (years) 50 ± 16 0.392 48 ± 16 0.403 52 ± 17 0.673
mPaP (mmHg) 50 ± 14 0.161 48 ± 14 0.162 48 ± 15 0.307
sPaP (mmHg) 71 ± 19 0.190 68 ± 18 0.195 70 ± 20 0.039
PVR (mmHg.l −1 .m −1 ) 7.8 ± 2.3 0.336 7.6 ± 2.6 0.292 8 ± 2.8 0.027
CI (l.m −1 .m −2 ) 2.6 ± 0.7 0.005 2.6 ± 0.6 0.016 2.6 ± 0.7 0.000
6MWT (m) 400 ± 160 0.136 423 ± 152 0.332 395 ± 141 0.168
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