Skin fibroblasts from individuals with Chediak-Higashi Syndrome (CHS) exhibit hyposensitive immunogenic response

Table 3 Gene expression profile of untreated CHS cells compared to untreated control cells

Gene symbol	Gene full name	Fold regulation	p-value
TLR1	Toll-like receptor 1	−3.25	0.00
CD14	CD14 molecule	−3.14	0.01
IL1R1	Interleukin 1 receptor, type I	−2.19	0.02
TLR2	Toll-like receptor 2	−8.04	0.06
TLR4	Toll-like receptor 4	−4.37	0.15
IL-6	Interleukin 6	2.50	0.18
IL-1β	Interleukin 1β	9.21	0.30
TLR-3	Toll-like receptor 3	4.03	0.31

Note: Table 3 corresponds to the volcano plot of Figure 1A. Genes above the dotted line have altered expression in CHS cells with statistical significance (p < 0.05); Genes below the dotted line were evaluated by RT-qPCR.

ISSN: 1750-1172