Figure 4
From: Oxidative stress and mitochondrial dysfunction in Kindler syndrome
Mitochondria distribution and function in KS keratinocytes. (a and b) Mito Tracker Red staining. Note the smeared mitochondria staining in KS keratinocytes (b) as compared to the control cells (a). (c and d) JC-1 staining. Note mitochondrial depolarization in KS keratinocytes as indicated by the decrease in the red/green fluorescence intensity ratio. (e) Quantification of JC-1 staining. Membrane potential reduction was statistically significant (*p < 0.05) after t-student test. Scale bars = 10 μm.