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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Oxidative stress and mitochondrial dysfunction in Kindler syndrome

Figure 1

Oxidative stress profile in Kindler Syndrome Keratinocytes. (a-c) GSSG/GSH ratio as redox profile coefficient was measured by fluorimetry in keratinocytes from patients SK1 (a), SK2 (b), and SK3 (c) and their matched controls. (d-f) GCLC and GCLM gene expression was analyzed by qPCR using GAPDH as reference gene in SK1 (d), SK2 (e), and SK3 (f) and their matched controls, using the method 2-ΔΔCt. (g-i) Malondialdehyde (MDA) levels were measured by HPLC-UV in SK1 (g), SK2 (h), and SK3 (i) and their matched controls. Results represent the means and SD from two independent experiments in triplicate samples. *p < 0.05: statistically significant difference from control value, after t-student test.

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