|
Variable
|
Normal persons
|
Marfan patients
|
P
1
|
|---|
|
(N = 123)
|
(N = 98)
|
|---|
|
Male gender
|
72 (59%)
|
42 (43%)
|
.022
|
|
Age (years)
|
42 ± 14 (16–77 )
|
39 ± 14 (14–79)
|
.113
|
|
Body weight (kg)
|
75 ± 14 (50–128)
|
74 ± 14 (45–115)
|
.398
|
|
Body height (m)
|
1.76 ± .1 (1.51–1.99)
|
1.85 ± .1 (1.58–2.10)
|
<.001
|
|
Body mass index (kg/m2)
|
24.2 ± 3.5 (16.3–39.9)
|
21.5 ± 3.6 (15.2–30.8)
|
<.001
|
|
Body surface area (DuBois; m2)
|
1.9 ± .21 (1.51–2.43)
|
1.96 ± .21 (1.51–2.51)
|
.040
|
|
Aortic root diameter (cm)2
|
3 ± .5 (1.9–4.2)
|
4.0 ± .7 (2–5.5)
|
<.001
|
|
Z-score of aortic root diameter
|
-.8 ± 1.6 (−6.2–1.9)
|
2.9 ± 2.3 (−4.4–7.4)
|
<.001
|
|
LV ejection fraction (%)
|
64 ± 6 (55–76)
|
55 ± 12 (21–78)
|
<.001
|
|
LVESD (mm/m2)
|
16 ± 3 (9–24)
|
18 ± 4 (10–36)
|
.005
|
|
LVEDD (mm/m2)
|
26 ± 3 (18–32)
|
27 ± 5 (20–48)
|
.009
|
|
Indexed left atrial diameter (mm/m2)
|
19 ± 3 (13–27)
|
19 ± 5 (8–32)
|
.339
|
- LV identifies left ventricle; LVEDD, indexed left ventricular end-diastolic diameter; LVESD, indexed left ventricular end-systolic diameter, and MPA ratio, ratio of main pulmonary artery diameter/aortic root diameter. 1Fisher’s exact test for nominal and categorical data and the Mann–Whitney test for continuous data. 2We obtained aortic root diameters in 103 normal persons and in 76 patients with Marfan syndrome.
