From: Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study
Miscarriage (n = 5) | Uncomplicated pregnancy (n = 6) | OR (95% CI) | |
---|---|---|---|
Age ≤ 30 years | 1 | 2 | 0.5 (0.03 – 8.06) |
Age >30 years | 4 | 4 | ref |
Primigravidae | 2 | 5 | 0.1 (0.01 – 2.2) |
Multigravidae | 3 | 1 | ref |
Non-recurrent TTP | 4 | 2 | 8.0 (0.5 – 127.9) |
Recurrent TTP | 1 | 4 | ref |
Time from previous TTP ≤24 months | 4 | 1 | 20.0 (0.9 – 429.9) |
Time from previous TTP >24 months | 1 | 5 | ref |
ADAMTS13 activity <25% in the first trimester* | 2 | 0 | ∞ (1.2 - ∞) |
ADAMTS13 activity ≥25% in the first trimester* | 1 | 5 | ref |
Positive anti-ADAMTS13 antibodies in the first trimester* | 3 | 0 | ∞ (4.1 - ∞) |
Negative anti-ADAMTS13 antibodies in the first trimester* | 0 | 5 | ref |