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Table 5 Risk estimates for miscarriage associated with demographic and clinical variables

From: Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study

 

Miscarriage (n = 5)

Uncomplicated pregnancy (n = 6)

OR (95% CI)

Age ≤ 30 years

1

2

0.5 (0.03 – 8.06)

Age >30 years

4

4

ref

Primigravidae

2

5

0.1 (0.01 – 2.2)

Multigravidae

3

1

ref

Non-recurrent TTP

4

2

8.0 (0.5 – 127.9)

Recurrent TTP

1

4

ref

Time from previous TTP ≤24 months

4

1

20.0 (0.9 – 429.9)

Time from previous TTP >24 months

1

5

ref

ADAMTS13 activity <25% in the first trimester*

2

0

∞ (1.2 - ∞)

ADAMTS13 activity ≥25% in the first trimester*

1

5

ref

Positive anti-ADAMTS13 antibodies in the first trimester*

3

0

∞ (4.1 - ∞)

Negative anti-ADAMTS13 antibodies in the first trimester*

0

5

ref

  1. *ADAMTS13 activity levels and anti-ADAMTS13 antibodies in the first trimester were available in 3 cases and 5 controls.