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Table 5 Risk estimates for miscarriage associated with demographic and clinical variables

From: Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study

  Miscarriage (n = 5) Uncomplicated pregnancy (n = 6) OR (95% CI)
Age ≤ 30 years 1 2 0.5 (0.03 – 8.06)
Age >30 years 4 4 ref
Primigravidae 2 5 0.1 (0.01 – 2.2)
Multigravidae 3 1 ref
Non-recurrent TTP 4 2 8.0 (0.5 – 127.9)
Recurrent TTP 1 4 ref
Time from previous TTP ≤24 months 4 1 20.0 (0.9 – 429.9)
Time from previous TTP >24 months 1 5 ref
ADAMTS13 activity <25% in the first trimester* 2 0 ∞ (1.2 - ∞)
ADAMTS13 activity ≥25% in the first trimester* 1 5 ref
Positive anti-ADAMTS13 antibodies in the first trimester* 3 0 ∞ (4.1 - ∞)
Negative anti-ADAMTS13 antibodies in the first trimester* 0 5 ref
  1. *ADAMTS13 activity levels and anti-ADAMTS13 antibodies in the first trimester were available in 3 cases and 5 controls.