Table 2 Biochemical data at diagnosis (excluding asymptomatic patients) and at last visit (all patients)
From: Urea cycle disorders in Spain: an observational, cross-sectional and multicentric study of 104 cases
Biochemical data * | At clinical onset (N = 91) | At last visit (N = 96) | Normal values |
|---|---|---|---|
Ammonia (μmol/L) | 298 (169-615) | 33 (27-42) | 10-55 (80**) |
Glutamine (μmol/L) | 1124 (859-1546) | 716 (545-908) | 350-650 |
Prothrombin activity (%) | 60 (32.6-82) | 91 (85-100) | 75-130 |
ALT (IU/L) | 76 (38-159) | 24 (16-34) | 5-39 |
AST (IU/L) | 53.5 (36.7-161) | 27.5 (19-37.2) | 5-37 |
Bilirrubin (mg/dL) | 0.60 (0.43-3.77) | 0.53 (0.30-0.80) | 0.20-1.10 |
Albumin (g/L) | 3.79 (3-4.41) | 4.30 (3.90-4.50) | 3.80-5.40 |
pH | 7.43 (7.36-7.46) | - | 7.35-7.45 |
Bicarbonate (mmol/L) | 21 (19-24) | - | 23-27 |