Table 2 Clinical characteristics of all reported infantile BP cases, including own patient cohort

Mean (median) age/age range

4.5 (4) months/1–12 months

Gender M/F

39/38 (4 unknown)

Extent of skin in involvement

• Localized/mild disease (+/− few disseminated plaques)

N = 10 (12.3%)

• Generalized/moderately severe and severe disease

N = 68 (83.9%)

• N/A

N = 3 (3.7%)

• Involvement of hands and feet

N = 81 (100%)

Involvement of oral mucosa (with generalized disease)

N = 12 (14.8%)

All children with oral lesions had generalized skin involvement

Severe disease N = 5

No of children vaccinated prior to onset

N = 25 (30.8%)

Latency between vaccination and onset of disease: 1 day - 4 weeks

• DPTP +/− others,

N = 22

• Rotavirus,

N = 2

• DPTP plus Rotavirus

N = 1

No of patients with a relapse

N = 12 (14.8%)

Outcome

• Cured

N = 76 (93.8%)

Patient had congenital immune deficiency

• In remission under treatment at time of report

N = 3 (3.7%)

• Still symptomatic at time of report

N = 1 (1.2%)

• Death

N = 1 (1.2%)