Skip to main content
Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Bullous pemphigoid in infants: characteristics, diagnosis and treatment

Figure 1

Clinical and diagnostic hallmarks of infantile BP. Patient 1 at initial presentation: A, urticarial plaques on the trunk. B, firm blisters and bullae on the hands and feet. C, D, Patient 1 after relapse with severe blistering on 2 mg/kg prednisolone daily. Direct immunofluorescence microscopy: E, linear IgG and F, linear C3c depositions along the basement membrane zone (white arrows, 200× original magnification). G, indirect immunofluorescence on salt-split skin reveals circulating IgG antibodies that bind to the blister roof, which is diagnostic for BP (white arrows, 200× original magnification).

Back to article page