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Figure 3 | Orphanet Journal of Rare Diseases

Figure 3

From: Clinical spectrum and long-term follow-up of 14 cases with G6PC3 mutations from the French severe congenital neutropenia registry

Figure 3

Bone marrow morphology in patients with G6PC3 congenital neutropenia. (A) Typical global bone marrow morphology: rich cellularity with predominant granulopoiesis (G), some erythroblasts (E), and one micromegakaryocyte (MK). (B) Predominant granulopoiesis with some myelocytes (M), very few metamyelocytes (MN), and a high number of mature neutrophils (N). (C) Details of neutrophils: hypersegmented appearance with thin opening between lobes and chromatin clumps. (D) Examples of micromegakaryocytes.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172