Figure 6

Influence of intronic variants on GLA processing. (A) Localization of the intronic variants IVS2-81_-77delCAGCC [rs5903184]), IVS4-16A>G [rs2071397] and IVS6-22C>T [rs2071228]). (B) GLA exons and denoted flanking introns (wild-type and variant). (C) Agarose gel separation of exon trapping products. wt: wild-type.