Skip to main content

Table 2 HRQOL scores of children with IEM and movement disorders compared to scores in healthy children

From: Rare inborn errors of metabolism with movement disorders: a case study to evaluate the impact upon quality of life and adaptive functioning

  IEM and movement disorders n = 24 Healthy Dutch population n = 87 t-value CI 95% p -value*
Mean value (SD) Mean value (SD)
Total score 49.63 (21.78) 87.60 (11.00) -8.21 -28.78 to -47.16 <0.001
Physical functioning 39.71 (24.56) 92.20 (9.10) -10.44 -43.31 to -63.67 <0.001
Emotional functioning 63.50 (23.18) 81.10 (17.40) -3.42 -7.38 to -27.82 <0.001
Social functioning 49.71 (29.18) 90.30 (14.00) -6.57 -25.32 to -52.86 <0.001
School functioning 51.29 (32.05) 82.50 (16.30) -4.49 -17.41 to -45.01 <0.001
  1. HRQOL scores were measured on the PedsQL 4.0 Generic Core Scales. Parent proxy-reports of children with IEM and movement disorders were compared to scores of healthy Dutch children [14].
  2. CI Confidence interval, IEM Inborn error of metabolism, SD Standard deviation, *significance level after Bonferroni-Holm correction for multiple comparisons.
  3. Bold text: statistically significant.