Neurological, psychiatric and visceral symptom onset in relation to diagnosis. Time interval from the onset of first recorded neurological, psychiatric and visceral symptoms to the diagnosis. Time at diagnosis = 0. The first number in brackets represents patients with symptom onset before diagnosis and includes index patients only. The second number represents the total patient number. Abbreviations: Del. milest. = delayed milestones; Cog. decline = cognitive decline; Psych. symptoms = psychotic symptoms; Behav. probl. = behavioural problems; Hep-spl.meg. = Hepatosplenomegaly; Prolong. jaund. = prolonged jaundice.