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Table 2 Analysis of atypical immunoreactive trypsin (≥65 ng/ml) in newborns in a Spanish region

From: Differences in immunoreactive trypsin values between type of feeding and ethnicity in neonatal cystic fibrosis screening: a cross-sectional study

Variable Total 13310 n(%)/x ± s AIT 196 (1.5%) n(%)/x ± s Not AIT 13114 (98.5%) n(%)/x ± s Adj. OR 95% CI (Adj. OR) p-value
Gender male 6861(51.5) 95(48.5) 6766(51.6) 0.88 0.66-1.17 0.385
Maternal origin:       
Spain 9994(75.1) 144(73.5) 9850(75.1) 1 1 0.219
Africa 953(7.2) 22(11.2) 931(7.1) 1.50 0.95-2.37  
South America 967(7.3) 9(4.6) 958(7.3) 0.63 0.32-1.25  
Rest of Europe 1061(8.0) 15(7.7) 1046(8.0) 0.88 0.51-1.52  
Asia 335(2.5) 6(3.1) 329(2.5) 1.21 0.52-2.82  
Maternal age (years):       
<20 358(2.7) 8(4.1) 350(2.7) 1.70 0.83-3.49 0.353
20-40 12531(94.1) 182(92.9) 12349(94.2) 1 1  
>40 421(3.2) 6(3.1) 415(3.2) 1.06 0.46-2.40  
Gestational age (weeks):       
<32 146(1.1) 6(3.1) 140(1.1) 1.45 0.49-4.25 0.137
32-37 1568(11.8) 13(6.6) 1555(11.9) 0.59 0.33-1.05  
>37 11596(87.1) 177(90.3) 11419(87.1) 1 1  
Feeding method:       
Natural 8698(65.3) 144(73.5) 8554(65.2) 1 1 <0.001
Mixed 1902(14.3) 16(8.2) 1886(14.4) 0.53 0.31-0.89  
Formula 2689(20.2) 30(15.3) 2659(20.3) 0.72 0.48-1.07  
Special 21(0.2) 6(3.1) 15(0.1) 21.88 6.92-69.14  
Days from extraction >20 47(0.4) 1(0.5) 46(0.4) 1.51 0.21-11.13 0.684
Temperature (°C) 18.7 ± 5.6 18.0 ± 5.2 18.8 ± 5.6 0.98 0.95-1.00 0.064
  1. Abbreviations: AIT atypical immunoreactive trypsin, Adj. OR adjusted odds ratio, CI confidence interval.
  2. Goodness-of-fit of the model: Χ2 = 53.19, p < 0.001.
  3. ORs were adjusted for: gender, maternal origin, maternal age, gestational age, feeding method, days from extraction and temperature.
  4. 2012-2013 data.