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Figure 4 | Orphanet Journal of Rare Diseases

Figure 4

From: Prognostic implication of morphology, cyclinE2 and proliferation in EBV-associated T/NK lymphoproliferative disease in non-immunocompromised hosts

Figure 4

Cyclin E2 expression was associated with high proliferation rate and poor outcome in TNKLPD. Significantly higher cyclin E2 expression was present in M-group compared to P-group patients (A, median expression of 42% compared with 8%, p = 0.0005). Patients with high tumor cyclin E2 expression of 15% or greater had statistically significant shorter survival compared with those with low cyclin E2 expression less than 15% (B, p = 0.0002). High cyclin E2 expression is highly correlated with high Ki-67 proliferation rate (C, spearman r = 0.73, p = 0.0006).

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