From: Management of endocrino-metabolic dysfunctions after allogeneic hematopoietic stem cell transplantation
Long-lasting basal insulin
3 methods for adjusting rapid-acting insulin
Retrospective ( sliding scale ) - the simplest- given dose according to pre-prandial blood glucose
Only when pre-prandial glucose >1.20 g/L or when the patient loses weight
- insulin dose according to postprandial glycaemia observed at the same time on preceding days.
- insulin dose based on counting carbohydrates - complex
- usually 2 detemir injections
- or a single glargine injection in the evening at a total dose of 0.3 to 0.5 U/kg/day.
- more complex to use but
- poorly suited to transient insulin therapy
- Any increase in pre-prandial glycaemia (particularly in the morning) >1.50 g/L necessitates an increase of 2 to 4 units in the dose of slow-acting insulin relative to the previous day.
- more appropriate if steroids use