Diagnosis
|
Positivity among
|
IDO-1
|
CXCR3
|
CXCL9
|
IL2RB
|
FOXP3
|
---|
SPTL
|
morphologically malignant cells in adipose tissue
|
14/19
|
15/21
|
15/15
|
9/14
|
0/9
|
++
|
++
|
+ + +
|
+ +
|
-
|
|
inflammatory infiltrate in dermis
|
11/19
|
2/21
|
4/14
|
9/14
|
7/9
|
++
|
+
|
+
|
+
|
+ or ++
|
Lupus erythematosus panniculitis (LEP)
|
inflammatory infiltrate
|
0/5
|
5/5
|
6/6
|
4/6
|
4/5
|
-
|
+
|
+ +
|
+
|
+
|
Erythema nodosum (EN)
|
inflammatory infiltrate
|
0/5
|
11/12
|
9/10
|
8/9
|
1/5
|
-
|
+ + +
|
+
|
+
|
+
|
- Number of positive cases/all cases studied.
- Grading of positive immunostaining: − below 10%, +10-25%, ++ 25-50%, and +++ over 50% of the cells (lymphocytes) expressing the given marker. To note, the positive cells were not always equally distributed in the tissue sections. LEP and EN have no morphologically malignant cells.