Total population | Carriers <50 Years | Carriers ≥50 Years | ||||
---|---|---|---|---|---|---|
Affected | Unaffected | Affected | Unaffected | Affected | Unaffected | |
Mutation type | ||||||
m.11778G > A (%) | 167 (66.0) | 190 (68.6) | 118 (66.3) | 78 (66.7) | 16 (80) | 60 (67.4) |
m.3460G > A (%) | 53 (20.9) | 49 (17.7) | 31 (17.4) | 24 (20.5) | 4 (20) | 12 (13.5) |
m.14484 T > C (%) | 33 (13.0) | 38 (13.7) | 29 (16.3) | 15 (12.7) | 0 (0) | 17 (19.1) |
Total | 253 | 277 | 178 | 117 | 20 | 89 |
Sex N, (%) | ||||||
Male | 194 (76.7) | 92 (33.2) | 134 (74.9) | 32 (27.4) | 15 (75.0) | 28 (31.5) |
Female | 59 (23.3) | 185 (66.8) | 45 (25.1) | 85 (72.6) | 5 (25.0) | 61 (68.5) |
Male/Female ratio | 3.3 | 0.5 | 3.0 | 0.37 | 3.0 | 0.46 |
Mean disease duration | 15.9 (16.16) | 10.71 (10.47) | 10.5 (19.12) | |||
VF-14 score (SD) | 25.1 (20.8) | 97.3 (7.1) | 25.14 (21.18) | 98.01 (5.22) | 18.06 (15.27) | 96.45 (8.91) |