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Table 1 Baseline characteristics of BCS patients with and without BD

From: Behcet’s disease in budd-chiari syndrome

  BCS with BD (n =14) BCS without BD (n =92) p
Age at BCS diagnosis, median (range) 33 (22–45) 38 (16–77) 0.086
Male gender, n (%) 11/14 (79%) 32/92 (35%) 0.003
Geographic origin    0.0002
Europe 6 (43%) 66 (73%)  
North Africa 8 (57%) 12 (13%)  
Type of outflow obstruction    
IVC occlusion, n (%) 10/14 (71%) 16/91 (18%) < 0.0001
HV occlusion alone, n (%) 4/11 (36%) 75/91 (82%) 0.002
Combined HV and IVC occlusion, n (%) 6/11 (55%) 15/91 (16%) 0.009
Number of hepatic veins thrombosed, median ± SD 2 3 0.017
1 HV thrombosed, n (%) 3/10 (30%) 5/91 (5%)  
2 HV thrombosed, n (%) 1/10 (10%) 13/91 (14%)  
3 HV thrombosed, n (%) 5/10 (50%) 72/91 (79%)  
Clinical features at baselinea, n (%)    
Ascites 6/13 (46%) 72/92 (78%) 0.036
Hepatomegaly 6/13 (50%) 55/92 (60%) 0.38
Splenomegaly 2/12 (17%) 51/92 (55%) 0.014
Abdominal pain 6/13 (46%) 62/92 (67%) 0.21
Hepatic encephalopathy 0/13 7/90 (8%) 0.59
Gastrointestinal bleeding 0/13 10/92 (11%) 0.36
Laboratory at baselinea    
ALT < 5 × ULN, n (%) 10/11 (91%) 60/92 (65%) 0.10
AST < 5 × ULN, n (%) 10/11 (91%) 63/92 (68%) 0.17
Bilirubinemia (μmol/l), med(min-max) 13 (6–38) 31 (7 – 207) < 0.0001
Albuminemia (g/l), med(min-max) 37(26–49) 35(19–52) 0.94
CRP level (mg/L), med(min-max) 85(7–238) 16(3–344) 0.003
Creatinemia (μmol/L), med(min-max) 80(44–120) 73(36–428) 0.34
Prothrombin Time < 70%, n (%) 5/11 (45.5%) 62/92 (67.4) 0.19
Thrombopenia (< 150.10 [9]/L), n (%) 2/12 (16.7%) 18/92 (19.6%) 1
Rotterdam BCS index 1 (0.0;1.2) 1.2 (0.0;3.9) 0.0007
  1. Abbreviations: ALT Alanine aminotransferase, AST Aspartate aminotransferase, BD Behcet’s disease, BCS Budd-Chiari Syndrome, CRP C reactive protein, HV Hepatic vein, IVC Inferior vena cava, Med Median, ULN Upper limit of normal.
  2. aIn BD patients, laboratory values at baseline were available in 11 patients for AST, ALT, creatinemia and CRP level, in 10 patients for albuminemia and in 12 patients for biliburinemia.
  3. In BCS patients without BD, laboratory values were available in 90 patients for bilirubinemia, in 73 patients for albuminemia, in 87 patients for creatinemia and 41 patients for CRP level.
  4. Bold indicates significant differences.