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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Atypical multisensory integration in Niemann-Pick type C disease – towards potential biomarkers

Figure 2

Nonparametric randomization plots for the individual-participant reaction time data for each Niemann-Pick type C patient. RTs in each of the unisensory conditions were compared against the multisensory RTs (middle and right columns), and against each other (left column). The observed differences in mean RT between Audio vs. AV, Visual vs. AV, and Audio vs. Visual (red line) were compared with reference distributions of differences that were derived by iteratively randomizing (10,000 times) between the two original data sets (i.e. individual-subject single trial RTs for 1) Audio and AV, 2) Visual and AV, and 3) Audio and Visual). Significant differences (p < .05) are indicated by an asterisk. The findings are mixed. In two of the three patients, any apparent multisensory speeding is not significantly faster than the faster of the two unisensory responses. However, in one of the patients (Participant 2), RTs to the AV condition are significantly faster compared to both unisensory inputs. This particular patient is showing strong evidence for the so-called redundant sensory effect, but this speeding does not violate the race model.

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