Figure 2
From: Effects of miglustat treatment in a patient affected by an atypical form of Tangier disease
3H-cholesterol efflux to Apo A-I in cultured skin fibroblasts. Cells were incubated under basal conditions (white bars) and in the presence of 22-hydroxycholesterol and 9-cis-retinoic acid (22OH/cRA) (black bars) to stimulate ABCA1 gene expression. Ctrl: healthy control cells; #Mo-4: patient with the clinical diagnosis of Tangier Disease described in this study; TDPK: control patient with Tangier Disease reported in a previous study [4].