Figure 3
From: Proposed guidelines for the diagnosis and management of methylmalonic and propionic acidemia
Neuroimaging finding in MMA: Male child with MMA (cblA defect). Follow-up MR imaging 6 months after acute deterioration shows residual T2 hyperintensity in the caudate nuclei and necrosis in the lentiform nuclei with reversal of abnormalities in the globus pallidi (A). There is CSF-like unrestricted diffusion in the lentiform nuclei on DWI (B) and ADC map (C) and elevated Cho on MR spectroscopy (D).