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Table 3 Contingency table and statistical analysis of hepatomegaly data

From: Clinical efficacy of Enzyme Replacement Therapy in paediatric Hunter patients, an independent study of 3.5 years

Group

Pre-post

McNemar test p-value

Positive Outcomes

Y-Y

Y-N

N-Y

N-N

Proportion

CI (95%)

A

3

3

4

1

1.0

0.36

(0.109, 0.692)

B

1

6

0

0

0.03*

0.86

(0.421, 0.996)

C

3

2

0

2

0.50

0.57

(0.184, 0.901)

A + B

4

9

4

1

0.27

0.56

(0.308, 0.785)

A + B + C

7

11

4

3

0.12

0.56

(0.349, 0.756)

  1. The category 'Positive Outcomes" includes both YES-NO (Y-N: improvement) and NO-NO (N-N: stabilization) cases. Confidence intervals, calculated by the Clopper and Pearson method and the p-value of McNemar test are reported. Statistically significant values (p < 0.05) are marked with an asterisk. Group A: n = 11, group B: n = 7, group C: n = 7.