Age group | Time point from start of ERT | n | Median (minimum-maximum) | p-value |
---|---|---|---|---|
A | 1 yr ± 4 m | 12 | 37.6 (7.8-76.0) | 0.0005* |
2 yrs ± 4 m | 9 | 29.4 (3.9-92.1) | 0.0039* | |
3 yrs ± 4 m | 7 | 24.5 (13.7-81.8) | 0.0156* | |
Last | 13 | 25.4 (5.7-79.2) | 0.0002* | |
B | 1 yr ± 4 m | 6 | 33.9 (17.1-88.1) | 0.0313* |
2 yrs ± 4 m | 4 | 19.5 (17.4-36.0) | 0.1250 | |
3 yrs ± 4 m | 4 | 19.2 (18.0-23.1) | 0.1250 | |
Last | 7 | 18.2 (14.6-55.8) | 0.0156* | |
C | 1 yr ± 4 m | 5 | 26.4 (8.9-38.8) | 0.0625 |
2 yrs ± 4 m | 4 | 16.5 (9.3-29.6) | 0.1250 | |
3 yrs ± 4 m | 5 | 26.4 (5.7-35.1) | 0.0625 | |
Last | 5 | 13.3 (5.1-28.2) | 0.0625 | |
A + B | 1 yr ± 4 m | 18 | 35.6 (7.8-88.1) | < .0001* |
2 yrs ± 4 m | 13 | 20.2 (3.9-92.1) | 0.0002* | |
3 yrs ± 4 m | 11 | 21.0 (13.7-81.8) | 0.0010* | |
Last | 20 | 24.0 (5.7-79.2) | < .0001* | |
A + B + C | 1 yr ± 4 m | 23 | 31.8 (7.8-88.1) | < .0001* |
2 yrs ± 4 m | 17 | 20.0 (3.9-92.1) | < .0001* | |
3 yrs ± 4 m | 16 | 22.0 (5.7-81.8) | < .0001* | |
Last | 25 | 18.2 (5.1-79.2) | < .0001* |