Table 2 Patient characteristics (entire study population and patients with vitD deficiency)

Age

- Mean age (years) (±SD)

28 (±20)

25 (±13)

- Children (less than15 years and 3 months)/adults : n (%)

19 (36)/34 (64)

5 (33)/10 (67)

Gender

- Female/Male : n (%)

35 (66)/18 (34)

9 (60)/6 (40)

Form of ichthyosis

- Non syndromic ichthyosis : n (%)

47 (88.7)

13 (86.8)

- Common ichthyoses

12 (22.6)

0 (0)

- Ichthyosis vulgaris

6 (11.3)

0 (0)

- Recessive X-linked ichthyosis

6 (11.3)

0 (0)

- Autosomal recessive congenital ichthyosis

29 (54.7)

11 (73.4)

- Lamellar ichthyosis

16 (30.2)

9 (60)

- Congenital ichthyosiform erythroderma

8 (15.1)

1 (6.7)

- Bathing suit ichthyosis

4 (7.5)

1 (6.7)

- Self-healing collodion baby

1 (1.9)

0 (0)

- Keratinopathic ichthyosis (epidermolytic ichthyosis)

3 (5.7)

1 (6.7)

- Other forms

3 (5.7)

1 (6.7)

- Erythrokeratodermia variabilis

1 (1.9)

0 (0)

- Congenital reticular ichthyosiform erythroderma

1 (1.9)

1 (6.7)

- Keratosis linearis - ichthyosis congenital – keratoderma

1 (1.9)

0 (0)

- Syndromic ichthyosis : n (%)

6 (11.3)

2 (13.2)

- Netherton syndrome

3 (5.7)

0 (0)

- KID syndrome

2 (3.7)

2 (13.2)

- Neutral lipid storage disease

1 (1.9)

0 (0)

Skin features

- Erythema (VAS) mean ± SD [range]

2.20 ± 2.5 [0 – 8.5]

2.57 ± 2.5 [0 – 8.5]

- Scaling (VAS) mean ± SD) [range]

4.25 ± 2.2 [1.5 – 9]

4.80 ± 2.6 [1.5 – 9]

Overall severity

- Mild to moderate/Severe to very severe : n (%)

38 (72)/15 (28)

7 (47)/8 (53)

Phototype

- I to III/IV to VI : n (%)

39 (74)/14 (26)

8 (53)/7 (47)

Sun exposure habits

- Avoiding strictly sun exposure : n (%)

21 (45)

6 (46)

Number of patients with missing data

6

2

Season of vitamin D measurement

- Winter – spring/Summer – autumn : n (%)

30 (57)/23 (43)

13 (87)/2 (13)

Treatments

- Systemic therapy (acitretin) : n (%)

8 (15)

4 (27)