Figure 1

Sensitivity of human ovarian cancer cells for chemotherapeutic compounds (A-C). SCCOHT-1^GFP cells, NIH:OVCAR-3^GFP and SK-OV-3^GFP cells were incubated with different concentrations of chemotherapeutic compounds for 72 h, respectively, and the proliferative capacity was measured by the fluoroscan assay. Analysis of a drug-dose–response to define IC50 concentrations for all compounds was performed using GraphPad Prism-6. For calculation of the drug-dose–response curves, the data were normalized to the cells-only control in culture medium and to the maximal solvent concentration control of the corresponding compound, respectively.