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Table 2 Correlations between the SARA, IDR-ICARS, BI, and IDR-BI scores and patients’ demographics

From: A 3-year cohort study of the natural history of spinocerebellar ataxia type 6 in Japan

 

SARA

IDR-ICARS

BI

IDR-BI

Age at onset

NS

NS

NS

NS

Age at registration

0.36b

0.43c

−0.45c

−0.57c

Disease duration

0.35b

0.45c

−0.35b

−0.44c

CAG repeat length of the expanded CACNA1A allelea

NS

NS

NS

NS

  1. Correlation coefficients are presented.
  2. Abbreviations: BI = Barthel Index; CACNA1A = the alpha 1A P/Q type voltage-dependent calcium channel gene; CAG = cytosine-adenine-guanine; ICARS = International Cooperative Ataxia Rating Scale; IDR = Intractable Diseases Research; NS = not significant; SARA = Scale for the Assessment and Rating of Ataxia.
  3. IDR-BI = total points of 6 items from the BI assessed by the IDR registry.
  4. IDR-ICARS = total points of 5 items from the ICARS assessed by the IDR registry.
  5. aData on the CAG repeat length were analyzed for 43 patients heterozygous for the expanded allele.
  6. bP < .05 (statistical analysis conducted with the Pearson correlation test).
  7. cP < .01 (statistical analysis conducted with the Pearson correlation test).