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Table 1 Variation in D-prevalence across age groups in very large cities in Ontario, Canada

From: Targeting under-diagnosis in hereditary hemorrhagic telangiectasia: a model approach for rare diseases?

City

Population size

Total number of confirmed HHT cases

D-prevalence for 20–49 year-olds (per 5000)

D-prevalence for ≥50 year-olds (per 5000)

London

267,145

14

0.22

0.31

Brampton

303,700

16

0.20

0.40

Hamilton

379,780

26

0.24

0.48

Mississauga

486,270

16

0.16

0.17

Ottawa

614,770

20

0.16

0.16

Toronto

1,947,455

134

0.25

0.48

Total

3,999,120

226

0.22*

0.38*

  1. Note: the combined adult population of these cities comprises 50 % of the entire adult population of Ontario; *denotes a statistically significant difference of p < 0.00005.
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172