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Table 1 Variation in D-prevalence across age groups in very large cities in Ontario, Canada

From: Targeting under-diagnosis in hereditary hemorrhagic telangiectasia: a model approach for rare diseases?

City Population size Total number of confirmed HHT cases D-prevalence for 20–49 year-olds (per 5000) D-prevalence for ≥50 year-olds (per 5000)
London 267,145 14 0.22 0.31
Brampton 303,700 16 0.20 0.40
Hamilton 379,780 26 0.24 0.48
Mississauga 486,270 16 0.16 0.17
Ottawa 614,770 20 0.16 0.16
Toronto 1,947,455 134 0.25 0.48
Total 3,999,120 226 0.22* 0.38*
  1. Note: the combined adult population of these cities comprises 50 % of the entire adult population of Ontario; *denotes a statistically significant difference of p < 0.00005.