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Table 1 Characteristics of 9 GD patients who developed a GD associated malignancy

From: Modelling Gaucher disease progression: long-term enzyme replacement therapy reduces the incidence of splenectomy and bone complications

Complication Treatment status at diagnosis Disease phase at diagnosis Genotype
Amyloidosis/MM ERT <2 years Multiple complications N370S/L444P
HCC ERT <2 years Multiple complications N370S/I260T
Amyloidosis/MM untreated Complication: Sx N370S/L444P
HCC ERT 6 years Complication: Sx R463C/?
Amyloidosis/MM ERT 2 years Multiple complications N370S/R257Q
Amyloidosis/MM ERT 15 years Multiple complications N370S/L444P
HCC ERT >17 years Multiple complications N370S/L324P
Amyloidosis/MM ERT 19 years Multiple complications N370S/G84GG
HCC ERT 18 years Multiple complications N370S/N370S