Table 2 GRD (N = 287) versus non-GRD (N = 2648) CKD population characteristics

Site

Number

Proportion of site

Number

Proportion of site

x2

Relative risk (95% Ci)

1

149

13.68%

940

86.32%

<0.0005

1.380 (1.221-1.560)

2

30

7.26%

383

92.74%

0.073

0.723 (0.509-1.027)

3

60

6.37%

882

93.63%

<0.0005

0.628 (0.498-0.791)

4

24

11.53%

184

88.46%

0.396

1.203 (0.801-1.809)

5

24

8.48%

259

91.52%

0.464

0.855 (0.573-1.275)

GRD

Non-GRD

GRD vs Non-GRD

Number

Proportion of GRD

Number

Proportion of Non-GRD

x2

Relative risk (95% CI)

Male

132

0.46

1440

0.54

0.007

0.738 (0.592-0.921)

Female

155

0.54

1208

0.46

0.007

1.354 (1.086-1.688)

GRD

Non-GRD

GRD vs Non-GRD

CKD stage

Number

Proportion of GRD

Number

Proportion of Non-GRD

x2

Relative risk (95% CI)

1

45

15.68%

134

5.06%

<0.0005

2.714 (2.052-3.591)

2

51

17.77%

277

10.46%

<0.0005

1.718 (1.298-2.273)

3a

48

16.72%

475

17.94%

0.628

0.926 (0.689-1.244)

3b

64

22.30%

887

33.50%

<0.0005

0.599 (0.458-0.782)

4

53

18.47%

685

25.87%

0.006

0.674 (0.506-0.898)

5

23

8.01%

182

6.87%

0.542

1.160 (0.776-1.734)

unknown

3

1.05%

8

0.30%

0.085

2.808 (1.063-7.417)

T Test/Mann–Whitney Test

Mean eGFR

49.72

40.35

t (2921) = 7.05, p <0.001

Median eGFR

45

37

U (2923) = 445087, Z = 5.3, p <0.001

GRD

Non-GRD

GRD vs Non-GRD

Mean age

52.6

69.3

t (2933) = 14.65, p <0.001

Median age

53.39

66.42

U (2935) = 545319, Z = 12.12, p <0.001

Age group

Number

Proportion of GRD

Number

Proportion of Non-GRD

x2

Relative risk (95% CI)

15-20

10

3.48%

8

0.30%

<0.0005

5.850 (3.813-8.977)

21-25

20

6.97%

20

0.76%

<0.0005

5.421 (3.896-7.543)

25-30

19

6.62%

40

1.51%

<0.0005

3.456 (2.346-5.091)

31-35

17

5.92%

59

2.23%

0.001

2.369 (1.535-3.656)

36-40

16

5.57%

81

3.06%

0.027

1.727 (1.088-2.741)

41-45

25

8.71%

89

3.36%

<0.0005

2.110 (1.465-3.039)

46-50

24

8.36%

118

4.46%

0.005

1.795 (1.224-2.631)

51-55

33

11.50%

140

5.29%

<0.0005

2.074 (1.493-2.881)

56-60

14

4.88%

233

8.80%

0.024

0.558 (0.331-0.940)

61-65

25

8.71%

296

11.18%

0.232

0.777 (0.524-1.152)

66-70

31

10.80%

373

14.09%

0.126

0.759 (0.531-1.085)

71-75

21

7.32%

441

16.65%

<0.0005

0.423 (0.274-0.652)

76-80

16

5.57%

350

13.22%

<0.0005

0.414 (0.253-0.678)

81-85

12

4.18%

282

10.65%

0.001

0.392 (0.223-0.690)

86-90

2

0.70%

107

4.04%

0.005

0.182 (0.046-0.721)

91-95

2

0.70%

10

0.38%

0.621

1.709 (0.480-6.087)

96-100

0

0%

1

0.04%

1

0.000 (0.000-0.000)