Table 3 Baseline characteristics of the Marfan syndrome patients and control group and balancing tests pre and post genetic matching

Sample size (N)

  before matching

892

26,645

–

–

  after matching

892

892

–

–

Mean age (years)

  before matching

28.95

50.50

0.389

<0.001

  after matching

28.95

28.90

0.002

0.996

% female

  before matching

40.70

50.45

–

<0.001

  after matching

40.70

40.70

–

1

Mean propensity score

  before matching

0.116

0.029

0.470

0.002

  after matching

0.116

0.116

0.002

0.999

Elixhauser comorbidities

  before matching

15 of 29 significantly different at p < 0.05

  after matching

0 of 29 significantly different at p < 0.05

Pharmacy-based classes

  before matching

16 of 30 significantly different at p < 0.05

  after matching

0 of 30 significantly different at p < 0.05