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Table 4 Frequency of APOE alleles in different studies

From: Sporadic inclusion body myositis: the genetic contributions to the pathogenesis

Study Country Number of alleles (cases/controls) ϵ2 allele (controls) ϵ3 allele (controls) ϵ4 allele (controls)
Garlepp et al.[84] Australia 28/344 0.07 (0.061) 0.69 (0.811) 0.29 (0.128)
Harrington et al.[86] UK 22/116 0 (0.086) 0.818 (0.767) 0.182 (0.147)
Love et al.[87] UK 82/5008 0.05 (0.08) 0.79 (0.79) 0.16 (0.13)
Askanas et al.[85] USA 22/70 0.09 (0.10) 0.86 (0.79) 0.05 (0.11)
Gossrau et al.[51] Germany 70/112 0.1 (0.036) 0.757 (0.848) 0.143 (0.116)
Needham et al.[48] Australia 114/344 0.044 (0.061) 0.825 (0.811) 0.132 (0.128)
Present study (our unpublished data)* UK, USA and two European countries 116/1540 0.07 (0.13) 0.77 (0.73) 0.16 (0.14)
  1. *All participants gave their written informed consent and the study was approved by the National Research Ethics Service (NRES) Committee London – Queen Square (REC reference: 12/LO/1557).