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Table 4 Frequency of APOE alleles in different studies

From: Sporadic inclusion body myositis: the genetic contributions to the pathogenesis

Study

Country

Number of alleles (cases/controls)

ϵ2 allele (controls)

ϵ3 allele (controls)

ϵ4 allele (controls)

Garlepp et al.[84]

Australia

28/344

0.07 (0.061)

0.69 (0.811)

0.29 (0.128)

Harrington et al.[86]

UK

22/116

0 (0.086)

0.818 (0.767)

0.182 (0.147)

Love et al.[87]

UK

82/5008

0.05 (0.08)

0.79 (0.79)

0.16 (0.13)

Askanas et al.[85]

USA

22/70

0.09 (0.10)

0.86 (0.79)

0.05 (0.11)

Gossrau et al.[51]

Germany

70/112

0.1 (0.036)

0.757 (0.848)

0.143 (0.116)

Needham et al.[48]

Australia

114/344

0.044 (0.061)

0.825 (0.811)

0.132 (0.128)

Present study (our unpublished data)*

UK, USA and two European countries

116/1540

0.07 (0.13)

0.77 (0.73)

0.16 (0.14)

  1. *All participants gave their written informed consent and the study was approved by the National Research Ethics Service (NRES) Committee London – Queen Square (REC reference: 12/LO/1557).