From: Pulmonary alveolar proteinosis in children on La Réunion Island: a new inherited disorder?
n/total (%)* | |
---|---|
Clinical characteristics | |
Dyspnea and/or tachypnea | 34/34 (100) |
Cough | 9/34 (26) |
Low SaO2 (<92%) or low PaO2 (<70 mmHg) | 17/34 (50) |
Crackles at pulmonary auscultation† | 15/34 (44) |
Digital clubbing | 13/34 (38) |
Failure to thrive (weight < - 2 SD) | 27/34 (79) |
Anorexia | 22/33 (67) |
Vomiting | 7/34 (21) |
Hepatomegaly | 19/34 (56) |
Splenomegaly | 10/34 (29) |
Biological characteristics | |
Anemia (Hb < 11 g/dL) | 20/32 (63) |
Hyperleukocytosis (≥15 000/mm3) | 17/34 (50) |
Thrombocytosis (≥450 000/mm3) | 17/30 (57) |
High IgG level | 29/32 (90) |
Hypoalbuminemia (<30 g/L) | 17/25 (68) |
Elevated AST | 18/31 (58) |
Elevated ALT | 10/30 (33) |
Elevated GGT | 16/25 (64) |
Elevated LDH | 21/23 (91) |